Greg Thurber has won a National Science Foundation Faculty Early Career Development (CAREER) Award. The objective of this award is to molecularly engineer stabilized alpha helices for generating efficient molecular imaging agents and intracellular therapeutics against currently undruggable targets. These molecules have unique properties blending classic small molecule drugs and larger biologics. The project will  quantify the relationship between the physicochemical properties of the helices and the cellular and in vivo distribution of these molecules. Unique binders with high affinity and stability will be screened using a novel cell surface display technique to develop new therapeutics and imaging agents.